You're a hunter/gatherer, eating what you kill. How has your system evolved over the last 1-2 million years to help you thrive in conditions of unpredicable food supply?
"As the food is digested, Nanook's insulin rises to allow amino acids from the protein to be absorbed into his tissues from his bloodstream. But wait, insulin also tells tissues to absorb glucose, and the meal contained virtually no carbohydrate. Nanook is in danger of hypoglycemia. Fortunately, his brain detects the palmitic acid from the meal and signals his tissues to become resistant to the glucose-transporting effect of insulin. This may also cause his liver to produce some glucose to make up for the modest amount that gets removed
from his bloodstream during the insulin spike. His blood glucose remains stable.
The next week, the herd of caribou has moved on and there's no prey in Nanook's territory. He has to live on his own body fat for two days while he hunts. Fortunately, human body fat is about 20% palmitic acid.
As fat is released into his bloodstream, the brain detects the palmitic acid and reduces peripheral insulin sensitivity. This helps Nanook's body conserve glucose and use his own body fat as fuel instead.
Over a wide range of fat, carbohydrate and calorie intakes, this system works to maintain stable blood glucose. These three scenarios all illustrate why palmitic acid would be helpful by causing temporary
insulin resistance in situations where blood glucose needs to be conserved."
http://wholehealthsource.blogspot.com/2009/09/palmitic-acid-and-insulin-
resistance.html
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