This is anecdotal, but consistent with a common theme if you read about the carbohydrate hypothesis for the diseases of civilization. The kicker, for me, is that giving up bread is like giving up sugar, in that there's absolutely no significant nutrition in either. They exist in the human diet to provide calories and pleasure - we don't need calories any longer, and it seems like the short term pleasure comes at a high risk of real displeasure.
"A patient would come to the office, for example, with a blood sugar of 118 mg/dl (in the pre-diabetic range) and the other phenomena of pre-diabetes or metabolic syndrome (high blood pressure, high inflammation/c-reactive protein, low HDL, high triglycerides, small LDL), and the characteristic wheat belly. Eliminate wheat and, within three months, they lose 30 lbs, blood sugar drops to normal, blood pressure drops, triglycerides drop by several hundred milligrams, HDL goes up, small LDL plummets, c-reactive protein drops.
People also felt better, with flat tummies and more energy. But they also developed benefits I did not anticipate:"
The author didn't mention the issue of OCD/addicitive tendencies associated with gluten, but that's another factor to consider.
http://heartscanblog.blogspot.com/2009/09/unexpected-effects-of-wheat-free-diet.html
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