This was a very interesting intervention study - the good kind - which compared the results for 150 women who were assigned to one of three dietary approaches - calorie restricted "mediterranean", calorie restricted low carb 2 times per week, or "eat all you want" low carb 2 times per week.
The result?
Data revealed that both intermittent, low-carbohydrate diets were superior to the standard, daily Mediterranean diet in reducing weight, body fat and insulin resistance. Mean reduction in weight and body fat was roughly 4 kilograms (about 9 pounds) with the intermittent approaches compared with 2.4 kilograms (about 5 pounds) with the standard dietary approach. Insulin resistance reduced by 22 percent with the restricted low-carbohydrate diet and by 14 percent with the “ad lib” low-carbohydrate diet compared with 4 percent with the standard Mediterranean diet.
Insulin has long been identified as a player in cancer growth, because many cancers run only on glucose (which they ferment for fuel), are more insulin sensitive than normal tissues, and are also more sensitive to insulin like growth factor one (aka IGF1). In short, a high glucose, and therefore high insulin human provides an ideal environment for a cancer to outgrow surrounding tissues.
These factors are of course another indicator of the validity of the paleolithic model as a guide for human health.
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