Thursday, September 9, 2010

Vytorin Again

"The really tough thing for the statinators and other worshipers at the alter of the lipid hypothesis to come to grips with is that the Enhance study showed that those subjects taking Vytorin reduced their LDL-cholesterol by 40 percent more than those taking the statin alone ( 58% drop on Vytorin - 41% drop on Zocor), yet plaque increased in the subjects on Vytorin. But do you hear any head scratching over this? Anyone saying, "whoa there, a lower cholesterol equals more plaque'? Any body at all (other than yours truly, of course) seizing on the obvious? Nope. Not a one. The cry of the herd is 'back to statins alone.'
Maybe it's just me, but I would like to think that if I believed with all my heart that LDL-cholesterol caused plaque formation, and then a study came along showing a huge decrease in LDL-cholesterol accompanied by an increase in plaque formation, that my faith might be a little bit shaken. But not so with the statinators."

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