Tuesday, December 14, 2010

Colpo on The Grain Debate

http://anthonycolpo.com/?p=852
This is a classic Colpo combo of rant and right - does a nice job dissecting more grain based pseudo science, which means he's at least useful in that regard!  While he makes mountains out of molehills, this is still an informative read.

"...let’s take a look at cancer. In the FeAST trial, patients who underwent phlebotomy to reduce their iron stores were 35% less likely to develop cancer. Among the study participants who did develop cancer, those in the iron reduction group had 61% lower cancer-specific and 51% lower all-cause mortality, respectively[1]. And that was with a woefully inadequate reduction of serum ferritin to only 80 mcg/dl (it was supposed to have been reduced to near-deficiency levels).

"So we know that blood withdrawal does lower iron and that it reduces the risk of cancer. There is a paucity of data examining the effect of IP-6 on cancer prevention or treatment in humans. However, in rodent studies, purified IP-6 dramatically reduces tumor incidence, whereas high cereal fiber diets providing a similar amount of IP-6 do not[2-4]. In human trials, increased wheat fiber intake has failed miserably to protect against colon cancer or adenomatous polyp formation[5].
"As a disease prevention strategy, the consumption of whole-grains fails miserably. Yeah, I know, you can cite a million-and-one epidemiological studies showing that whole-grains are associated with lower rates of every known ailment under the sun. However, a fundamental rule of science (that many PhDs evidently forget the minute they graduate) is that association is not the same as causation. Due to their uncontrolled nature, epidemiological studies are hopelessly prone to confounding from a vast array of variables. Controlled clinical trials, a far more reliable form of evidence, routinely show whole-grains to do a whole lot of nothing when it comes to disease prevention and amelioration.
"As for your absurd claim that whole-grains contain enough minerals to negate the “so-called toxins”…crikey, where do I begin? First of all, your dismissive description of “so-called toxins”indicates an unwillingness to acknowledge the very real and well-documented anti-nutrient content of grains and legumes. I strongly suggest you read up on the existence and effects of phytate, lectins, enzyme inhibitors, and the vitamin-blocking glucosides that exist in these foodstuffs."

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