Tuesday, March 8, 2011

Taubes in Oz

If as we speculate the natural state of humankind is one of health - cancer unusual, heart/vascular diseases VERY rare, obesity unheard of, as were: gout, acne, autoimmune diseases, depression,
Alzheimer's, ALS, Parkinson's, etc - then it would be more accurate to say that carb restriction isn't so much protective as it is corrective.  It doesn't protect you from cancer, it simply stops contributing to those things which result in a tumorigenic environment (for example, through proper blood sugar regulation).  Perhaps that's a matter of semantics, but in that it helps to think more clearly about the situation, it can be a helpful distinction.  For example, next time you note someone who speculates about the cancer or heart disease protective benefits of "this that or the other", I suggest instead you consider that the natural state of affairs is for "this that or the other" not to happen - and if you don't stuff yourself with high density carbs, it will be much less likely for you, too. 
The rest of this post from Gary's blog - http://www.garytaubes.com/2011/03/dose-of-intervention-land-of-dr-oz/ - is well worth a read if you like the kinds of concepts we delve into in my blog.  A small excerpt:

" ... we get high blood glucose by consuming carbohydrate rich foods, which end up as glucose (a carbohydrate) in our blood stream. We also tend to have high blood glucose when we have a condition called insulin resistance, which is the underlying defect in obesity, diabetes and heart disease.  When Lehningers says insulin inhibits fatty acid mobilization that’s pretty much the equivalent of what Williams is saying about insulin inhibiting lipolysis.
The point of both is simple. Insulin puts fat in fat cells. That’s what it does. And our insulin levels, for the most part, are determined by the carb-content of our diet — the quantity and quality of the carbohydrates consumed. (Or if Jenny Brand Miller and her colleagues are right, also by our fat content — the lower the fat in the diet, the higher the insulin and vice verse.) The way to get fat out of fat cells and burn it, which is what we want to do with it, is to lower insulin. This has been known since the early 1960s.
One point I make in Why We Get Fat is that we all respond to this carbohydrate/insulin effect differently. Some of us can eat carbohydrate-rich meals and burn them off effortlessly. We’re the ones (like Oz) who partition the carbs we consume into energy. (This is the fuel gauge metaphor that I use in WWGF and that Oz’s producers reproduced wonderfully on the show.) And some of us partition the carbs we consume into fat for storage, and that partitioning depends on a lot of different enzymatic and hormonal factors — mostly relating to insulin and LPL as Williams Textbook of Endocrinology said).

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